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Although alienation is an essential characteristic of all [[subjectivity]], [[psychosis]] represents a more extreme form of alienation.
Lacan coined the term ''[[extimacy]]'' to designate the nature of this alienation, in which [[alterity]] inhabits the innermost core of the subject.
Lacan devotes the whole of chapter 16 of [[The Four Fundamental Concepts of PsychoanalysisSeminar_XI|The Seminar, Book XI, The Four Fundamental Concepts of Psychoanalysis]] (1964a) to a discussion of alienation and the related concept of [[separation]].