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<blockquote>The crudest of the methods of influencing the [[body]], but also the most effective, is the chemical one: that of intoxication ... The services rendered by intoxicating substances in the [[struggle ]] for [[happiness ]] and in warding off misery rank so highly as a benefit that both individuals and races have given [[them ]] an established [[position ]] within their [[libido]]-[[economy]]. It is not merely the immediate gain in [[pleasure ]] which one owes to them, but also a measure of that independence of the outer [[world ]] which is so sorely craved.<ref>{{C&D}} Ch. 2</ref></blockquote>